Hormones and Mineral Elements Associated with Osteoporosis in Postmenopausal Women in Eastern Slovakia
Osteoporosis is a multifactorial disease that results in reduced quality of life, causes decreased bone strength, and changes in their microarchitecture. Mostly postmenopausal women are at risk. In our study, we measured anthropometric parameters of postmenopausal women (104 women of control group – CG and 105 women of osteoporotic group - OG) and determined TSH hormone levels and PTH as well as mineral elements - Ca, P, Mg and enzyme alkaline phosphatase. Through the correlation analysis in CG, we have found association based on age and BMI, P and Ca, as well as Mg and Ca; in OG we determined interdependence based on an association of age and BMI, age and Ca. Using the Student's t test, we found significantly important differences in biochemical parameters of Mg (p ˂ 0,001) and TSH (p ˂ 0,05) between CG and OG.
 V. Palička, J. Blahoš, S. Býma, “Osteoporóza: Doporučený diagnostický a léčebný postup pro všeobecné praktické lékaře.” Online. Available: http://www.svl.cz/files/files/Doporucene-postupy-2008-2012/osteoporoza-2011-novelizace.pdf.
 E. M. Lewiecki, “To Treat or Not to Treat: Reducing Fracture Risk in Postmenopausal Women,” The Female Patient, vol. 37, no. 1, pp. 1-16.
 N. K. Arden, R. W. Keen, J. S. Lanchburg, T. D. Spector, T. D., Polymorphism of the vitamin D receptor gene do not predict quintitative ultrasound of the calcaneus or hip axis lenght, ”Osteoporosis International, vol. 6, no. 4, pp. 334-337.
 J. Payer, M. Borovský, P. Jackuliak, K. Brázdilová, Z. Killinger, E. Némethová, D. Čierny, A. Baňárová, S. Tomková, M. Kužma, J. Kollerová, “Osteoporóza pri vybraných ochoreniach”. Bratislava, Herba 2014. p.192, ISBN 978-80-89631-19-3.
 L. W. Turner, J. E. Taylor, S. Hunt, “Predictors for osteoporosis diagnosis among postmenopausal women: results from a national survey,” J. Women Aging, vol. 10, no. 3, pp.79-96.
 E. Kamycheva, R. Jorde, J. Sundsfjord, “Serum parathyroid hormone level is associated with body mass index”, European Journal of Endocrinology, vol. 151, pp. 167-172.
 A. Solanki, S. Bansal, S. Jidal, V. Saxena, U. S. Shukla, “Relationship of serum thyroid stimulating hormone with body mass index in healthy adults,” Indian. J. Endocrinol. Metab., vol. 17, no. 3, pp. 167-169.
 C. M. Kitahara, E. A. Platz, P. W. Ladenson, P. W. (ed.), “Body Fatness and Markers of Thyroid Function among U. S. Men and Women.” Online. Available:http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0034979.
 P. Garnero, P. D. Delmas, “Assessment of the serum levels of bone alkaline phosphatase with a new immunoradiometric assay in patients with metabolic bone disease”, Journal of Clinical Endocrinology and Metabolism, vol. 77, no. 4, pp. 1046-1053.
 Klinická biochémia, “Referenčné hodnoty biochemických parametrov u dospelých. Online. Available: http://www.klinickabiochemia.sk/download/biochemia.pdf, October 2017.
 A. L. Tranquilli, E. Lucino, G. G. Garzetti, C. Romanini, “Calcium, phosphorus and magnesium intakes correlate with bone mineral content in postmenopausal women,” Gynecological Endocrinology. Online. Available:http://www.researchgate.net/publication/15138867_Calcium_phosphorus_and_magnesium_intakes_correlate_with_bone_mineral_content_in_postmenopausal_women.