Our study was designed to highlight changes in
certain biochemical parameters (CH, TG, HDL, GOT, GPT, LDL and
CRP), obese women infertile fertile witnesses and research potential
pathophysiological link between obesity and infertility in this
population of women. This practical work was focused on a
population of 24 obese women infertile, compared to controls,
subjects without any pathology causing disruption of parameters to
be studied to determine the contribution of obesity in the etiology of
infertility. The assay results revealed a highly significant difference
between the two groups in serum CH, TG, HDL, TGO and TGP (P
<0.0001) and in the rate of LDL (p = 0.0017) and CRP (p = 0.02).
The present study indicates that obesity is associated with infertility,
but no direct pathophysiological link between obesity and infertility
has been determined. Further in-depth studies are needed to
determine the exact mechanism by which overweight leads to female
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