The variations in the arteries have been drawing attention of anatomists for a long time because of their clinical significance. The brachial artery is the principal artery of the arm which is the continuation of the axillary artery from the lower border of the Teres Major. It terminates into the radial and ulnar arteries below the elbow joint at the neck radius. The present study aims at exploring the clinical significance of the high termination of the brachial artery. During the routine cadaveric dissection of the arm, for the undergraduate students of medicine at our university, we observed a high bifurcation of the radial and the ulnar artery at the midshaft of the humerus. The median nerve was seen passing between these two junctions. Further, the course and the relations of this artery were studied. The accurate knowledge regarding these kinds of variation in the blood vessels is mandatory for planning of designing. General physicians, surgeons and radiologists should keep in mind the variations in the branching pattern of the arteries in their daily medical, diagnostic and therapeutic procedures to avoid complications in diagnostic and surgical procedures.
 Standring S. Gray S (2008) Anatomy (40th Edn) Spain, Churchill Livingstone, Elsevier pp: 830-835.
 Williams PL. Gray’s anatomy. 38th ed. Philadelphia: Elsevier Churchill Livingstone; 1995.
 Chummy S, Sinnatamby. Vessels and Nerves of Arm: Brachial Artery in Last's Anatomy regional and applied. Churchill Livingstone. 2006; 11: 61.
 Hollinshead WH. Anatomy for Surgeons. New York: Harper and Row Publishers; 1969; 2: 150-152.
 Bidarkotimath S, Avadhani R, Kumar A. Primary pattern of arteries of upper limb with relevance to their variations. Int. J. Morphol. 2011; 29(4). p. 1422-1428.
 Bidarkotimath S, Avadhani R, Kumar A, An anatomical study of primary pattern of arteries of upper limb with relevance to their variations. NUJHS. 2012; 2(1) p. 08-14.
 Dong Zhan, Yi Zhao, Jun Sun, Eng-Ang Ling, George W Yip (2010) High origin of radial arteries: a report of two rare cases. The Scientific World Journal 10: 1999-2002.
 Sikka A, Jain A. Bilateral variation in the origin and course of the vertebral artery. Anatomy Research International. 2012; 2012:1-3. (DOI:10.1155/2012/580765).
 Baeza AR, Nebot J, Ferreira B et al. An anatomical study and ontogenic explaination of 23 cases with variations in the main pattern of the human brachio-antebrachial arteries.J Anat1995;187:473-39.
 Anuradha L, Prabhu LV, Kumar A. Report on an anomalous pattern in the upper limb with its anatomical and clinical implication. J Anat Soc India, 2001,50 (1):69-98.
 Keith L Moore, Persaud T V N, Mark G Torchia. Before we are born: Essentials of embryology and birth defects. 8th Edition. Saunders; 2012. ISBN: 978-1437720013.
 Anson, B. J: Morris. Human Anatomy in; The cardiovascular system-Arteries and veins. Thoms, M. Edr. Mc Grow Hill Book c. New York.pp708-724(1966).
 De Garis CF, Swartley WB. The axillary artery in white and Negro stocks. Am J Anat. 1928:41; 353-97.
 Muller E (1903) Beitra$ge zur Morphologie des Gefa$sssystems. I. Die Armarterien des Menschen. Anatomische Hefte 22,377-575.
 Karlsson S, Niechajev I A (1982) Arterial anatomy of the upper extremity. Acta Radiologica 23, 115-121.
 Kian K, Shapiro JA, Salman L, et al. High brachial artery bifurcation: clinical considerations and prac- tical implications for an arteriovenous access. (Semin Dial. 2012;25(2):244-247.
 Gupta J, Jain R, Patil M. A study of brachial artery with high up division and its clinical significance. Int J Bioassays 2012; 1: 116-8.
 Chakravarthi KK. Gantzer’s muscle an accessory muscle of the forearm -Its Anatomical Variations and Clinical Insight. Int J Chemical and Life Sciences. 2013; 02: 1199-1203.
 Fuss FK, Matula CW, Tschabitscher M. Die Arteria brachialis superficialis. Anatomischer Anzeiger 1985; 160: 285-94.
 Singer E. Embryological pattern persisting in the arteries of the arm. Anat Record 1933,55:403-9.
 Williams PL, Bannister LH, Berry M. N, Collins P, Dyson M, Dussek JE, Ferguson MWJ. Gray’s Anatomy. 38th Ed. New York: Churchill Livingstone, 1995. 1538-15407.
 Adib A Aughsteen, Hasan M Hawamdeh, Muzahim Al-KHAYAT (2011) Bilateral variations in the branching pattern of brachial artery. International Journal of Anatomical Variation 4:167-170.
 Clinical practice guidelines for vascular access. Am J Kidney Dis. 2006;48 Suppl 1: S176-247.
 Okoro IO, Jiburum BC, Rare high origin of the radial artery: A bilateral, symmetrical case. Niger J Surg Res 2003; 5: 70-2.